Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H.
نویسندگان
چکیده
In the presence of Mn2+, reverse transcriptase of both human immunodeficiency virus and murine leukemia virus hydrolyzes duplex RNA. However, designating this novel activity RNase D conflicts with Escherichia coli RNase D, which participates in tRNA processing. On the basis of its location in the RNase H domain, we propose that this novel retroviral activity be redesignated RNase H*.
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ورودعنوان ژورنال:
- Journal of virology
دوره 68 3 شماره
صفحات -
تاریخ انتشار 1994